Evolutionary history is the focus of my posts for a while, and what better place to start than CRISPR? Last week, Emmanuelle Charpentier and Jennifer Doudna’s work in using CRISPR for gene editing made news headlines – this is the first time the Nobel Prize in Chemistry has been awarded to two women. The future […]
CRISPR Gene and The Nobel Prize in Chemistry Read More »
This is Marie-Claire King (born 1946), and just reading about her accomplishments makes me tired. Besides earning her Ph.D. from UC Berkeley, she has six other honorary doctorates in science from the most prestigious universities in the world. From her work in discovering the genetic foundations of breast cancer, schizophrenia, and hearing loss, to her
Marie-Claire King and Genetic Studies Read More »
Historians are frequently enchanted by things discarded as useless by the general public. But I think anyone interested in evolution would find the study of non-gene coding DNA fascinating, including the scientist featured here. This is Susumu Ohno, one of the United States’ foremost geneticists and evolutionary biologists, and he came up with the term
Susumu Ohno’s “Junk DNA” Read More »
“The Persistence of Memory” is one of artist Salvador Dali’s most recognizable paintings. The surrealist style is perfectly adapted to depicting the ways our minds preserve our memories — they are suggestive, dreamlike, warpable. For however imperfect or relativistic our memories might be, we owe them for much of our sense of identity.How we humans
Salvador Dali and the Arc Gene Read More »
Charles Darwin’s idea of Natural Selection as the key driver of evolution has been demonstrated many times over. However, in the century and a half since his lifetime, scientists have added onto his theories as various scientific discoveries have been made. Perhaps no one has reframed the picture of Darwinian evolution as much as the
Lynn Margulis and Eukaryotic Cells Read More »
It’s almost Halloween, dear readers, so you’ll be able to suss out my theme for this week without a hitch. On that note, I cannot believe that I have not yet done a post on Elizabeth Bathory, aka “the Blood Countess”.So here’s her story: born into an aristocratic Hungarian family in 1560, Elizabeth Bathory was
Elizabeth Bathory – “The Blood Countess” Read More »
What was it about Eastern Europe in the 1700s that brought about so many stories of Vampires? Some scholars note that Western European countries like Britain might have enjoyed these legends because they could make people feel civilized — those “eastern places” were rural, Catholic, superstitious, and backward in the minds of nationalist Brits.However, there
The Blood Disorder Porphyria and Vampirism Read More »
Those who know me, know that each year in lieu of holiday cards, I write historically themed Christmas carols. And this year, I give you the following, sung to the tune of “Good King Wenceslas”.When the plague spread all about/ thirteen-forty seven.Buboes pussing, fevers out/ Time to bury your kin.Philip tried to find the cause/
A Bubonic Plague Inspired Christmas Carol Read More »
This week’s stories focus on a subject in science history which is indeed topical across the world right now: the discovery of how the human immune system works. And to begin, I am introducing the image of this young girl, named Myrtis by the Greek archaeologists who reconstructed her appearance after excavating a mass grave
The Plague of Athens and the Immune System Read More »
Today on December 14, 2020, a critical care nurse in New York became the first American to receive the COVID vaccine. This begins a period of highly anticipated vaccine delivery in the weeks to come. The photo here harkens to another moment in American history when folks waited with bated breath for a cure for
The “Great Race of Mercy” for a Diphtheria Cure in Alaska Read More »
Shown here are Doctors Pear Kendrick and Grace Eldering, and together they developed the first successful vaccine against the childhood disease pertussis, or Whooping Cough.Whooping Cough is of course characterized by the sound of the hollow, forced, and unremitting chest cough that mostly younger people endured until the 20th-century development of a vaccine: it killed
Doctors Pear Kendrick and Grace Eldering Read More »
This week’s posts feature great moments in the history of immunology. Although the death of Vizzini (and corresponding survival of the hero Westley due to his years of building up immunity to iocaine powder, among the deadlier and fictitious poisons known to man) in _The Princess Bride_ might be famous in terms of cultural history,
The Antibody Serums of Shibasaburo Kitasato and Emil von Behring Read More »
In this last post for the week to focus on great moments in immunology, I feature a rare time when biologists actually got their naming system right.Featured here is an Ancient Roman copy of a Greek statue featuring Artemis. Although usually known as the Goddess of the Hunt and wilderness, the moon, and female chastity,
Scientists Despina Moshous and the Artemis Protein Read More »
In _Star Trek II: The Wrath of Khan_, the famous first lieutenant Spock airily quips to Dr. McCoy that “as a matter of cosmic history, it has always been easier to destroy than to create.” At the end of the film, the Vulcan sacrifices his life to prevent the destruction of the entire crew, because
Vaccinologist Maurice Hilleman and Helping the World Read More »
This barber’s pole may look like a quaint form of advertisement, reminiscent of a candy cane. However, it’s got a pretty sick story behind it.You probably know that medicine in the Middle Ages was not informed by the scientific method, and that hygiene, anatomy, and physiology weren’t understood. A good reason for cutting open a
The Barber Pole and Medieval Times Read More »
We are (I hope) appropriately dismissive at the ridiculous bogus discussions concerning the treatment of COVID-19 that have appeared in the media. Hydroxychloroquine, bleach, “Plandemic,” blah blah blah quackery. It’s a good thing to be appalled by those who tout cures which lack scientific merit. And so perhaps it would be well to have a
Dr. Albert Adams and His “Curative Machines” Read More »
Today we use the word “scurvy” as a general adjective for something that is corrosively destructive, like “religious bigotry was a scurvy of the Medieval Church.” Of course, these were the attributes of the OG disease, which blighted many people — but notably sailors — until a cure was found in the 1700s.Many of us
James Lind and Curing Scurvy in the 1700s Read More »
Queen Elizabeth I of England (d. 1603) ruled her country for decades through an era of extreme religious strife and against the will of many who thought, as the Protestant leader John Knox, that “It is more than a monstre in nature that a Woman shall reigne and have Empire above a Man . .
Queen Elizabeth I and Her “Queen’s Touch” Read More »
This disgusting, but hardly pornographic, illustration of a monk with open lesions on his penis is illustrative of the horrific pandemic of Syphilis that emerged in Europe in the late 15th century. Causing sores on genitalia in its first phase, the disease eventually results in ulcers, hair loss, and physical dismemberment among other things before
Epidemic of Syphilis in the 15th-Century Read More »
For centuries, Europeans’ #1 go-to treatment for the disease Syphilis was an administration of mercury. Physicians managed it via theraputic fumigation, through injections, and as topical creams – often in the form of mercurous chloride, called “sweet mercury” or “calomel”. As the 16th-century poem “Syphilis” notes: “All men concede that mercury’s the best/ Of agents that will
Medieval Syphilis Treatment (With Mercury) Read More »
